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Winter 2003
This information effective for Winter 2003. Check with instructor the first day of class for any changes.
Chemistry
[CHEM-080G] [CHEM-163B] [CHEM-240F]
80G. Bioethics in the 21st Century: Science, Business, and Society (Also offered as Philosophy 80G)
Instructors:
E. Suckiel & D. Deamer
Course Description:
The purpose of this course is to present and analyze ethical and social issues related to recent and widely influential advances in scientific research and biotechnology. It is designed to be of interest to students from all disciplines at UCSC. Guest speakers, distinguished experts in their fields, will join the instructors to consider the major ethical questions that have arisen from research in genetics, medicine, and the industries supported by this knowledge. This includes issues such as the ethics of animal experimentation, the morality of genetically modified crops, the promise and dangers of the human genome project, and the appropriate use of medical technologies.
Underlying our discussions will be an exploration of ways to articulate an appropriate conception of human beings and their place in the wider environment in which they live.
Required
Textbook (at Bay Tree Bookstore):
Tom Beauchamp and LeRoy Walters: Contemporary Issues in Bioethics, 6th edition.
163B. Thermodynamics and Kinetic Theory
Winter 2003
Instructor: Frank Andrews
Office: 317 Thimann
Phone: 459-2776
E-mail: andrews@chemistry
MWF 11:00–12:10
p.m.
Kresge 327
Short Course Description: Macroscopic thermodynamics and chemical kinetics for chemistry and biochemistry students who are expected to understand this material and use it for basic problem-solving, in their careers and their future undergrad and graduate education.
Text: Physical Chemistry, 3rd edition, R. A. Alberty and R. J. Silbey, John Wiley (chaps 1–8 and 18).
Quizzes and Exams: On every Friday except the first one, we will have either a short, 10-minute quiz at the end of class over the homework due that day, or we will have a midterm exam during the entire class period. For midterms and final (but not for quizzes), you can bring a single 8 1/2 x 11 inch sheet of paper with whatever you want on both sides of it, so long as you have personally done the writing and have not used a xerox machine to reduce the printing in size.
Note: The final exam will be at the time scheduled in the class schedule. If you cannot be in Santa Cruz to take that exam, do not enroll in the course.
Homework: There will be homework assignments due each Friday except the first of the term. The homework is for your benefit; it will not be graded.
Reader:
In addition to the text, which by the way will also be the text for
Chem 163C, if you are planning to go on, there is a reader which you will
want to get. It contains all the homework assignments and the worked-out
homework problems, plus a few other things of interest.
240F.
Selectivity and Strategy in Organic Synthesis
First 5 Weeks of
Winter Quarter 2003
TTh 12:00 - 1:45, 101 Thimann Labs
Instructor:
Rebecca Braslau
Office: Thimann 337, tel. 459-3087
Discussion Section: Wed. nights, 7:00 pm, Thimann 391, on January 15,
22, and 29
Course Description:
This is a 5-week course designed to follow Chemistry 240E, Modern Synthetic Reactions, offered by Professor Singaram. Prerequisite: 240E or consent of instructor
Assignments and Exams: There will be two exams: a midterm worth 100 pts on January 28, and a final exam worth 150 points on February 6. Three sets of homework (15 pts per set) will be assigned during the half quarter and should be turned into Rebecca's mailbox by 10:00 am on Wednesday, the day of the discussion section. Attendance at the discussion sections on Wednesday nights is mandatory.
No single
text will be used, although the following reference books are available
in the library:
- March,
Advanced Organic Chemistry
- Noyori,
Asymmetric Catalysis in Organic Synthesis
- Ager,
Asymmetric Synthetic Methodology
- Mulzer,
Organic Synthetic Highlights
- Fuhrhop
& Penzlin, Organic Synthesis: Concepts, Methods and Starting
Materials
- Seyden-Penne,
Chiral auxiliaries and ligands in asymmetric synthesis
- Morrison, Asymmetric synthesis Vol. 4 (contains a list of optically active starting materials)
The following topics will be covered:
Introduction
Literature and References
Starting Materials
Retrosynthetic Analysis
Selectivity
Selected
Reactions and Processes
Cyclizations
Baldwin's Rules
Thorpe-Ingold Effect
Cationic, Anionic, Radical & Organometallic Cyclizations
Other 5-Membered Ring Synthesis
Pauson-Khand
Carbonyl Condensations
Nazarov Cyclization
Palladium TMM
[3 + 2] Dipolar Cycloadditions
Control
of Stereochemistry
Relative Diastereoselectivity
Ring Systems
Acyclic StereocontrolFelkin-Ahn, Cram Chelation Control
Aldol Stereochemistry
Allylation of Carbonyls
Reconnective Strategy
Absolute
Stereochemistry
Relative Diastereoselectivity using Optically Pure Materials
Chirons
Classic Resolution
Chiral AuxiliariesEnantioselectivity
Stoichiometric Asymmetric Induction
Kinetic Resolution
Catalytic Asymmetric InductionAsymmetric Amplification
Synthetic
Strategy
Convergence
Atom Economy
Strategic Bonds
Biomimetic Strategy
Key Reaction Strategy
Formal Synthesis
Computers