Chemistry - Winter 1998

Chem 1M. This is the 2-unit chemistry lab designed to go with Chem 1B. You must either have previously passed 1B or be taking 1B in the winter in order to take 1M. Be sure to attend the first lab lecture (scheduled in the class schedule). At that time, you will fill out a form saying which times you are free, and within a few hours we will post your assignment to a 3-hour lab period. Both the lab lectures and the lab period are required. The lab manual will be obtainable from the Copy Center.

Chem 1N. This is the 2-unit chemistry lab designed to go with Chem 1C. You must eithr have previously passed 1C or be taking 1C in the winter in order to take 1N. Be sure to attend the first lab lecture (scheduled in the class schedule). At that time, you will fill out a form saying which times you are free, and within a few hours we will post your assignment to a 3-hour lab period. Attendance at both the lab lectures and the lab period are required. The lab manual is the same as the one you are using this Fall quarter (if you are taking 1M this term). If you are not taking 1M this term, the 1N manual will be available from the Copy Center.

CHEM 108B, "Organic Chemistry" Tuesday, Thursday 10:00-11:45 am Classroom Unit II

Instructor: Dr. Rebecca Braslau
Office: Thimann 337, tel. 459-3087, e-mail: braslau@chemistry
Office Hours: TBA
Teaching Assistants: TBA

Discussion Sections:

Homework is to be turned in and returned at your discussion section. Attendance and participation in your discussion section will be considered in your final evaluation.

John McMurry, "Organic Chemistry," 4th edition, Brooks/Cole Publishing Co.: Pacific Grove, CA, 1996; Susan McMurry, "Study Guide and Solutions Manual for Organic Chemistry," 4th edition, Brooks/Cole Publishing Co.: Pacific Grove, CA, 1996. A molecular model kit (any brand).

A current e-mail address is required. Announcements, corrections and assignments will be sent to you by e-mail. You are responsible for anything announced by e-mail just as if it were announced in lecture. There will be a web page at http://www.chemistry.ucsc.edu/teaching/Winter98/Chem108B for the class. Questions on course material can be sent to the Prof. Braslau at braslau@chemistry by e-mail, although I strongly encourage you to come to office hours in person when possible.

A list of assigned problems will be handed out at the beginning of the quarter, to be turned in at the designated dates. Since you will have the solution manual, the problems should be completed and corrected before being turned in for credit. The neatness and correctness of the original answers will not be of concern, rather the completeness in doing the assigned problems will be.

I strongly encourage you to make use of the office hours and discussion sections to discuss problems, exercises or concepts that are not clear. Two 1 3/4 hour exams (100 pts each) will take place on February 3 and March 3, 1998. The Final Exam (200 pts) will be held on Thursday, March 19 at 4:00 - 7:00 pm. If you have documented disability-related accommodation requests, please see me during office hours at least three weeks before each exam. All students should plan to be here for the exams: NO MAKE-UP EXAMS WILL BE ADMINISTERED. Please Note: Cheating on exams will absolutely Not be tolerated. No "warnings" will be given.

Date Topic; Text Chapter

Jan 8 Nuclear Magnetic Resonance Spectroscopy; 13

Jan 13 Alcohols and Thiols; 17

Jan 15 Alcohols and Thiols, Ethers, Epoxides and Sulfides; 17, 18

Jan 20 Ethers, Epoxides and Sulfides, Intro to Carbonyl Chemistry; 18, p.705

Jan 22 Aldehydes and Ketones; 19

Jan 27 Aldehydes and Ketones, Carboxylic Acids; 19, 20

Jan 29 Carboxylic Acid Derivatives; 21

Feb 3 First Exam Chapters 13, 17-20

Feb 5 Carboxylic Acid Derivatives, Carbonyl Alpha-Substitution Reactions; 21,22

Feb 10 Carbonyl Alpha-Substitution Reactions; 22

Feb 12 Carbonyl Condensation Reactions; 23

Feb 17 Exchange Day: no lecture for 108B

Feb 19 Aliphatic Amines; 24

Feb 24 Arylamines and Phenols; 25

Feb 26 Carbohydrates; 26

March 3 Second Exam Chapters 21-25

March 5 Carbohydrates; 26

March 10 Amino Acids, Peptides and Proteins; 27

March 12 Amino Acids, Peptides and Proteins; 27

March 17 Lipids; 28

March 19 Final Exam 4:00-7:00 p.m comprehensive

(former Chemistry 8M)

Continuation of 108 L, the main emphasis of this class are spectroscopic techniques such as infrared (IR) and nuclear magnetic resonance (NMR) which are the chemist's extended eyes. Students learn to obtain and interpret their own spectra as a routine part of their experimental work. They also gain further insight into gas chromatography, thin layer chromatography, and organic synthesis through extensive practice. Most of the experiments in this class have a direct relation to the bio-sciences, such as the synthesis and analysis of analgesics, analysis of milk and synthesis of thyroid-hormone related compounds.

The second part of the experimental organic chemistry course. The students will learn techniques such as column chromatography, refractometry, polarimetry, IR, and NMR. A challenging class with many applications in the biosciences. The students will gain first hand experience in problem-solving in the laboratory.

Revised 7/12/04.