Chemistry and Biochemistry

Lower-Division Courses

1A. General Chemistry. F
First term of an integrated study of general chemistry. Course 1A is suitable for people who have not studied chemistry. Covers a range of topics including the atomic structure of matter, molecules, chemical reactions, acids and bases, gases and nuclear chemistry. Lecture: 3-1/2 hours; discussion: 1-1/4 hours. Students are expected to use algebra to solve problems. Prerequisite(s): completion of the Chemistry Placement Examination. (General Education Code(s): IN, Q.) T. Schleich

1B. General Chemistry. F,W
Second term of an integrated study of general chemistry. Coverage includes quantum mechanics, the hydrogen atom, many-electron atoms and chemical periodicity, and elementary covalent bonding. Lecture: 3-1/2 hours, discussion: 1-1/4 hours. Prerequisite(s): course 1A or passing the 1B placement exam, or a preparatory chemistry course at another college or university, or a grade of 4 on the AP chemistry examination. (General Education Code(s): IN, Q.) F. Andrews, E. Switkes

1C. General Chemistry. W,S
Third term of an integrated study of general chemistry. Coverage includes thermochemistry, thermodynamics, chemical kinetics, chemical equilibrium in solution, oxidation-reduction and electrochemistry, nuclear chemistry. Lecture: 3-1/2 hours; discussion: 1-1/4 hours. Prerequisite(s): course 1B. (General Education Code(s): IN, Q.) F. Andrews

1M. General Chemistry Laboratory (2 credits). F,W
Laboratory sequence illustrating topics covered in courses 1B-1C, respectively, and important experimental techniques. Laboratory: 3 hours; lecture: 1-1/4 hours. Students are billed a materials fee. Course 1M offered fall and winter; 1N offered winter and spring. Prerequisite(s): course 1A or passing the 1B placement exam, course 1B or concurrent enrollment in 1B; satisfaction of the Subject A writing requirement is highly recommended. Enrollment limited to 144. The Staff

1N. General Chemistry Laboratory (2 credits). W,S
Laboratory sequence illustrating topics covered in courses 1B-1C, respectively, and important experimental techniques. Laboratory: 3 hours; lecture: 1-1/4 hours. Students are billed a materials fee. Course 1M offered fall and winter; 1N offered winter and spring. Prerequisite(s): course 1M, course 1C or concurrent enrollment in 1C. The Staff

80A. Chemistry of Nutrition: Concepts and Controversy. *
A brief description of the relevant chemical and physical properties of the main classes of foods, vitamins, and minerals. Discussion of their digestion, sources, metabolism, recommended daily allowances, and effects of deficiencies. High school chemistry strongly recommended as preparation. Offered in alternate academic years. (General Education Code(s): T2-Natural Sciences.) A. Fink

80G. Bioethics in the Twenty-First Century: Science, Business, and Society. F
Serves science and non-science majors interested in bioethics. Guest speakers and instructors lead discussions of major ethical questions having arisen from research in genetics, medicine, and industries supported by this knowledge. (Also offered as Philosophy 80G and Biomolecular Engineering 80G.) (General Education Code(s): T2-Natural Sciences.) E. Suckiel

80H. Introduction to Wines and Wine Chemistry. *
Introduction to scientific aspects of winemaking and wine sensory evaluation. Overview of wines emphasizing chemical and biological principles appropriate for both non-science and science students. Aspects of wine presented including history, viticulture, fermentation, winery operations, and physiology of wine consumption. Students are billed a materials fee. (General Education Code(s): T2-Natural Sciences.) P. Crews

80L. Introduction to Chemistry of Wines and Musts (2 credits). *
An integrated course exploring elementary aspects of wine evaluation and modern winemaking. Topics: effects of grape varieties, vineyard locations, production techniques, aging practices on wine quality, and winemaking. Survey of commercial wine styles and lab methods of wine component analysis provide insights on how fine wines are made and analyzed. Students are billed for a materials fee. Prerequisite(s): concurrent enrollment in or completion of course 80H. Enrollment limited to 32. P. Crews

99. Tutorial. F,W,S
Students submit petition to sponsoring agency. May be repeated for credit. The Staff

99F. Tutorial (2 credits). F,W,S
Students submit petition to sponsoring agency. The Staff

Upper-Division Courses

103. Biochemical Structures, Reactions, and Energetics. W
Introduces biochemical molecules that compose all living organisms. Focus on structure and function relationships in chemical components of cells, primary enzyme-catalyzed reactions of metabolism. Chemical principles of cell function at molecular level; molecular structure of nucleic acids discussed. Prerequisite(s): courses 1B and 1C; 108A-B or 112A-B-C or 7. T. Schleich

108A. Organic Chemistry. F,W
An integrated study of fundamental organic chemistry, with emphasis on materials especially relevant to the biological sciences. Students with credit for course 112A cannot receive credit for course 108A; students with credit for 112B or 112C cannot receive credit for 108B. Lecture: 3-1/2 hours, discussion: 1-1/4 hours. Prerequisite(s): course 1C or 4B or a grade of 5 on the AP chemistry examination. J. Konopelski, C. Bernasconi

108B. Organic Chemistry. W,S
An integrated study of fundamental organic chemistry, with emphasis on materials especially relevant to the biological sciences. Students with credit for course 112A cannot receive credit for course 108A; students with credit for 112B or 112C cannot receive credit for 108B. Lecture: 3-1/2 hours, discussion: 1-1/4 hours. Prerequisite(s): course 108A or 112A. P. Crews, The Staff

108L. Organic Chemistry Laboratory (2 credits). F,W
Laboratory experience in organic chemistry associated with courses 108A-108B, respectively. Designed to introduce the student to the many techniques associated with organic chemistry while affording an opportunity to explore the concepts discussed in the lecture material. Laboratory: 4 hours, lecture: 1-1/4 hours. Students are billed a materials fee. Prerequisite(s): courses 1C/N and 108A or concurrent enrollment. D. Palleros

108M. Organic Chemistry Laboratory (2 credits). W,S
Laboratory experience in organic chemistry associated with courses 108A-108B, respectively. Designed to introduce the student to the many techniques associated with organic chemistry while affording an opportunity to explore the concepts discussed in the lecture material. Laboratory: 4 hours, lecture: 1-1/4 hours. Students are billed a materials fee. Prerequisite(s): courses 108A/L and 108B or concurrent enrollment. D. Palleros

112A. Organic Chemistry. F
An integrated study of fundamental organic chemistry, including principles, descriptive chemistry, synthetic methods, reaction mechanisms, and compounds of biological interest. These courses are coordinated with 112L-M-N respectively and are to be taken concurrently with them. Students with credit in course 108A can receive credit for courses 112B and 112C but not for 112A; students with credit in 108B cannot receive credit for 112B or 112C. Lecture: 3-1/2 hours; optional discussion section: 1-1/4 hours. Prerequisite(s): course 1C or 4B or a grade of 5 on the AP chemistry examination; and course 1N or 4M. Students should be concurrently enrolled in course 112L. Enrollment limited to 100. The Staff

112B. Organic Chemistry. W
An integrated study of fundamental organic chemistry, including principles, descriptive chemistry, synthetic methods, reaction mechanisms, and compounds of biological interest. These courses are coordinated with 112L-M-N respectively and are to be taken concurrently with them. Students with credit in course 108A can receive credit for courses 112B and 112C but not for 112A; students with credit in 108B cannot receive credit for 112B or 112C. Lecture: 3-1/2 hours; optional discussion section: 1-1/4 hours. Prerequisite(s): courses 108A/L or 112A/L (preferred). Students should be concurrently enrolled in course 112M. Enrollment limited to 100. R. Braslau

112C. Organic Chemistry. S
An integrated study of fundamental organic chemistry, including principles, descriptive chemistry, synthetic methods, reaction mechanisms, and compounds of biological interest. These courses are coordinated with 112L-M-N respectively and are to be taken concurrently with them. Students with credit in course 108A can receive credit for courses 112B and 112C but not for 112A; students with credit in 108B cannot receive credit for 112B or 112C. Lecture: 3-1/2 hours; optional discussion section: 1-1/4 hours. Prerequisite(s): courses 112B/M. Students should be concurrently enrolled in course 112N. Enrollment limited to 100. R. Lokey

112L. Organic Chemistry Laboratory (2 credits). F
Laboratory experience in organic chemistry and associated principles. Experiments involve the preparation, purification, characterization, and identification of organic compounds and make use of modern as well as classical techniques. These courses are coordinated with 112A-B-C respectively, and are to be taken concurrently with them. For courses 112L and 112M: lecture: 1-1/2 hours and laboratory: 4 hours; for course 112N: lecture: 1-1/4 hours and laboratory: 8 hours. Students are billed a materials fee. Prerequisite(s): courses 1C/N. Students should be concurrently enrolled in course 112A. Enrollment limited to 100. D. Palleros

112M. Organic Chemistry Laboratory (2 credits). W
Laboratory experience in organic chemistry and associated principles. Experiments involve the preparation, purification, characterization, and identification of organic compounds and make use of modern as well as classical techniques. These courses are coordinated with 112A-B-C respectively, and are to be taken concurrently with them. For courses 112L and 112M: lecture: 1-1/2 hours and laboratory: 4 hours; for course 112N: lecture: 1-1/4 hours and laboratory: 8 hours. Students are billed a materials fee. Prerequisite(s): courses 108A/L or 112A/L (preferred). Students should be concurrently enrolled in course 112B. Enrollment limited to 100. D. Palleros

112N. Organic Chemistry Laboratory (2 credits). S
Laboratory experience in organic chemistry and associated principles. Experiments involve the preparation, purification, characterization, and identification of organic compounds and make use of modern as well as classical techniques. These courses are coordinated with 112A-B-C respectively, and are to be taken concurrently with them. For courses 112L and 112M: lecture: 1-1/2 hours and laboratory: 4 hours; for course 112N: lecture: 1-1/4 hours and laboratory: 8 hours. Students are billed a materials fee. Prerequisite(s): courses 112B/M. Students should be concurrently enrolled in course 112C. Enrollment limited to 100. D. Palleros

122. Principles of Instrumental Analysis. F
A laboratory course designed to develop familiarity with techniques and instrumentation used in analytical chemistry, emphasizing determination of trace inorganic species. Primary emphasis on applications utilizing the absorption or emission of electromagnetic radiation and on voltammetry. Topics include molecular UV-visible absorption and fluorescence spectrometry; atomic absorption, emission and fluorescence spectrometry; and various forms of voltammetry. Lecture: 2 hours; laboratory: 8 hours. Students are billed a materials fee. Prerequisite(s): satisfaction of the Subject A and Composition requirements, course 108B or 112C. (General Education Code(s): W.) P. Mascharak

143. Organic Chemical Structure and Reactions. F
Advanced topics such as the chemistry of terpenes, steroids, synthetic polymers, alkaloids, reactive intermediates, and reaction mechanisms are treated. Lecture: 4 hours. Prerequisite(s): course 108B or 112C. B. Singaram

146A. Advanced Laboratory in Organic Chemistry (2 credits). S
Designed to expose students to advanced laboratory techniques in organic chemistry. Experiments carry a research-like format and cover the areas of natural products and reaction chemistry. Modern methods of organic analysis are emphasized including chromatographic methods and organic structure determination by spectroscopy. Laboratory: 8 hours. Students billed a materials fee. Prerequisite(s): courses 108B/M or 112C/N. Enrollment limited to 16. R. Braslau

146B. Advanced Laboratory in Inorganic Chemistry (2 credits). S
Designed to expose students to advanced synthetic and spectroscopic techniques in inorganic chemistry. Examples include anaerobic manipulations, characterization of inorganic materials through spectral assignments and synthesis of coordination and organometallic complexes. Lecture: 1-1/4 hours; laboratory: 8 hours. Students billed a materials fee. Prerequisite(s): courses 108B/M or 112C/N; 163A. T. Holman

146C. Advanced Laboratory in Physical Chemistry (2 credits). S
Provides advanced and more open-ended laboratory experience in the areas of thermodynamics, kinetics, spectroscopy, and computer simulations. Lecture: 1-1/4 hours; laboratory: 4 hours. Students are billed a materials fee. Prerequisite(s): course 161B and 163B. Enrollment limited to 20. J. Zhang

146D. Advanced Laboratory in Computational Chemistry (2 credits). *
Designed to give experience in advanced computational chemistry through open-ended research-type problem solving. Covers molecular graphics, molecular mechanics, semi-empirical and abinitio calculations applied to conformational analysis, reaction predictions, and drug design. Prerequisite(s): course 108B or 112C. Enrollment limited to 40. The Staff

151A. Chemistry of Metals. S
Fundamental topics of inorganic chemistry are presented at the level of the standard texts of field. Special emphasis is given to maintain breadth in the areas of metallic, nonmetallic, and biological aspects of inorganic chemistry. Lecture: 3-1/2 hours; discussion: 1-1/4 hours. Prerequisite(s): courses 108B/M or 112C/N; 163A; students should be concurrently enrolled in course 151L. T. Holman

151B. Chemistry of the Main Group Elements. F
Fundamental aspects of inorganic chemistry of main group elements are discussed. The emphasis is placed on the chemistry of nontransition elements including noble gases and halogens. In addition, students are exposed to the concepts of extended structures, new materials, and solid-state chemistry. Lecture: 3-3/4 hours. Prerequisite(s): courses 108B/M or 112C/N, and 163A. Recommended for chemistry majors. S. Williamson

151L. Inorganic Chemistry Laboratory (2 credits). S
Laboratory experience in inorganic chemistry. Experiments involve the preparation, purification, and characterization of inorganic compounds. In addition, experiments are designed to illustrate fundamental principles in inorganic chemistry and are coordinated with lectures in course 151A. Laboratory: 4 hours per week. Students are billed a materials fee. Prerequisite(s): courses 108B/M or 112C/N; 163A; students should be concurrently enrolled in course 151A. T. Holman

163A. Quantum Mechanics and Basic Spectroscopy. F
A detailed introduction to quantum theory and the application of wave mechanics to problems of atomic structure, bonding in molecules, and fundamentals of spectroscopy. Prerequisite(s): course 1C or 4B, Physics 5A-B-C or 6A-B-C and Mathematics 11C or 22 or 23B. Physics 6C can be taken concurrently. G. Millhauser

163B. Thermodynamics and Kinetic Theory. W
Fundamentals of thermodynamics and applications to chemical and biochemical equilibria. Prerequisite(s): course 1C or 4B, Physics 6A or 5A, and Math 11C or 22. I. Benjamin

163C. Kinetic Theory and Reaction Kinetics, Statistical Mechanics, Spectroscopic Applications. S
Introduction to statistical mechanics, kinetic theory, and reaction kinetics and topics in spectroscopy. Prerequisite(s): courses 163A and 163B. J. Zhang

164A. Physical Chemistry Laboratory I: Data Analysis (2 credits). F
Introduction to data analysis and statistical treatment of errors for physical chemistry experiments. Emphasizes the use of computers for problem solving and data analysis of one required laboratory report. Lecture: 1 hour; laboratory: 4 hours. Prerequisite(s): course 1C or 4B; Physics 6A-B-C or 5A-B-C; Mathematics 11C or 22. R. Anderson

164B. Physical Chemistry Laboratory II (2 credits). W
Provides laboratory experience in the areas of thermodynamics, kinetics, and spectroscopy. Lecture: 1 hour; laboratory: 4 hours. Students are billed a materials fee. Prerequisite(s): course 164A. J. Zhang

180A. Senior Research. F
An individually supervised course with emphasis on independent research. Multiple-term course extending over two or three quarters; the grade and evaluation submitted for the final quarter apply to all previous quarters. Students submit petition to sponsoring agency; may not be repeated for credit. The Staff

180B. Senior Research. W
An individually supervised course with emphasis on independent research. Multiple-term course extending over two or three quarters; the grade and evaluation submitted for the final quarter apply to all previous quarters. Students submit petition to sponsoring agency; may not be repeated for credit. The Staff

180C. Senior Research. S
An individually supervised course with emphasis on independent research. Multiple-term course extending over two or three quarters; the grade and evaluation submitted for the final quarter apply to all previous quarters. Students submit petition to sponsoring agency; may not be repeated for credit. The Staff

199. Tutorial. F,W,S
Students submit petition to sponsoring agency. May be repeated for credit. The Staff

199F. Tutorial (2 credits). F,W,S
Students submit petition to sponsoring agency. May be repeated for credit. The Staff

Graduate Courses

200A. Advanced Biochemistry: Biophysical Methods. F
An introduction to the theory, principles, and practical application of biophysical methods to the study of biomolecules, especially proteins and nucleic acids. Emphasis on spectroscopic techniques. Topics include magnetic resonance, optical spectroscopy, fast reaction techniques, crystallography, and mass spectrometry. R. Bogomolni

200B. Advanced Biochemistry: Protein Structure and Function. W
A detailed discussion of protein chemistry, ranging from the structure, thermodynamics, and folding of proteins to the relationship between structure and function, and encompassing the methods used to determine such information. G. Millhauser

200C. Advanced Biochemistry: Structure and Function of Nucleic Acids. *
A variety of contemporary problems in biochemistry and molecular biology are investigated in a detailed manner. Lecture: 3-1/2 hours. The Staff

231. Enzyme Mechanisms and Kinetics. *
A study of enzyme kinetics, mechanisms, and factors involved in enzymic catalysis. Lecture: 3-1/2 hours. Offered in alternate academic years. A. Fink

234. Bioinorganic Chemistry. W
The role played by transition metals in biological systems is discussed through application of the principles of coordination chemistry and inorganic spectroscopy. Topics include metalloproteins involved in oxygen binding, iron storage, biological redox reactions, and nitrogen fixation, as well as metal complexes of nucleic acids. Lecture: 4 hours. Prerequisite(s): courses 151A/L, 163A; and Biochemistry and Molecular Biology 100A. P. Mascharak

238. Topics in Biophysical Chemistry. *
A discussion of the application of selected topics in biophysical chemistry to contemporary problems in biochemistry and molecular biology. Lecture: 3-1/2 hours. Offered in alternate academic years. T. Schleich

240A. Kinetics and Mechanisms of Organic Reactions (3 credits). F
Basic principles and methods of the kinetic study of reaction mechanisms are covered, including linear free energy relationships. Theories are examined concerning how reactions choose a mechanism. C. Bernasconi

240B. Combinatorial and High-Throughput Methods in Synthetic Chemistry
(3 credits). W
Focuses on solid phase synthetic methods as applied to synthesis of compound libraries. Explores advances in laboratory automation, library synthesis, encoding and decoding schemes, and computational approaches to library design and virtual screening. (Formerly Structure and Reactivity. ). Enrollment restricted to seniors and graduate students. R. Lokey

240C. Organic Structure Analysis from Spectra (3 credits). *
Determination of 2-D and 3-D structure and functionality of organic molecules from spectroscopic properties, including nuclear magnetic resonance, infrared, ultraviolet-visible and mass spectroscopy. P. Crews

240D. Computational Organic Chemistry (3 credits). S
Current computational methods used to predict reaction products, evaluate conformational energies, and correlate NMR spectra with conformations are examined. Molecular mechanics treatments are compared to semiempirical AM1 calculations. The Staff

240E. Modern Synthetic Methods (3 credits). F
An advanced study designed to provide the background and insight to enable the student to compare and contrast new reagents and reactions with existing methods. Prerequisite(s): course 143. B. Singaram

240F. Selectivity and Strategy in Organic Synthesis (3 credits). S
An advanced study on the use of chemoselectivity, regioselectivity, and stereoselectivity in organic transformations. Strategic planning in approaching the synthesis of complex molecules focuses primarily on retrosynthetic analysis and stereochemical control. Prerequisite(s): course 240E. R. Braslau

240G. Bioorganic Chemistry of Amino Acids and Peptides (3 credits). *
Chemistry of amino acids and secondary structure of amino acid polymers (peptides and proteins) discussed. Special emphasis placed on structure and function of the distinct amino acid side chain functionality as it contributes to structure and function. J. Konopelski

246. Advanced Topics in Organic Chemistry.
A graduate course covering advanced topics in organic chemistry. Topics vary from year to year. The Staff

246A. Organic Reactions and Molecular Orbital Theory. *
Qualitative molecular orbital concepts, especially concerning aromaticity, orbital symmetry, and perturbation theory, and their application toward interpretation of reactivity and mechanism. Lecture: 3-1/2 hours. Prerequisite(s): courses 273 and 240A. Offered in alternate academic years. May be repeated for credit. The Staff

246B. Marine Organic Chemistry. *
A survey of organic natural products from marine sources. Organic chemical structural families unique to marine organisms are outlined. Pathways of their synthesis and interconversions; their role in the marine environment; approaches to their analysis; the distribution of organics in seawater. Lecture: 3-1/2 hours. Prerequisite(s): courses 108B/M or 112C/N. Offered in alternate academic years. May be repeated for credit. P. Crews

246C. Computers and Information Processing in Chemistry. *
An introduction to digital computers and their applications in chemistry. Includes Monte Carlo, artificial intelligence, pattern recognition, modeling, simulation, and optimization problem-solving methods. Applications to include structural analysis, spectroscopy, organic synthesis, and kinetics. Lecture: 3-1/2 hours; laboratory: 1-1/2 hours. Offered in alternate academic years. May be repeated for credit. The Staff

246F. Organoboranes in Organic Synthesis. *
An introduction to organoborane chemistry and its applications to synthetic organic chemistry, including principles, synthetic methods, reaction mechanisms, and asymmetric synthesis. A variety of topics including allylboration, boron-enolates, and asymmetric reductions are discussed. Enrollment restricted to seniors and graduate students. Offered in alternate academic years. May be repeated for credit. B. Singaram

246G. Heterocyclic Chemistry. *
Advanced study of synthesis and reactions of heterocyclic organic compounds; particular emphasis on structures with important medicinal value from natural products or pharmaceutical research. Prerequisite(s): course 143 or approval of instructor. J. Konopelski

246H. Organic Free Radical Chemistry. *
Covers a range of topics including radical stabilization, rates of fundamental radical reactions, methods of radical generation, synthetic applications of free radicals, persistent radicals, and some aspects of free radicals in biology. Prerequisite(s): course 143 or permission of instructor. R. Braslau

246I. Advanced Mechanistic Chemistry and Solution Kinetics. *
Kinetic approach to selected topics in mechanistic chemistry with emphasis on structure-reactivity relationships in organic as well as inorganic and biochemical systems. Discussion of significance and treatment of kinetic data illustrated with examples from various branches of chemistry. Prerequisite(s): permission of instructor. C. Bernasconi

256A. Advanced Topics in Inorganic Chemistry. *
Advanced topics in inorganic chemistry are presented. Topics covered vary from year to year, and are announced in advance. Possible topics include A) organometallic chemistry; B) structural methods in inorganic chemistry; C) solid-state chemistry. Prerequisite(s): courses 151A/L and 146B or graduate standing. The Staff

256B. Advanced Topics in Inorganic Chemistry. *
Advanced topics in inorganic chemistry are presented. Topics covered vary from year to year, and are announced in advance. Possible topics include A) organometallic chemistry; B) structural methods in inorganic chemistry; C) solid-state chemistry. Prerequisite(s): courses 151A/L and 146B or graduate standing. The Staff

256C. Advanced Topics in Inorganic Chemistry. S
Advanced topics in inorganic chemistry are presented. Topics covered vary from year to year, and are announced in advance. Possible topics include A) organometallic chemistry; B) structural methods in inorganic chemistry; C) solid-state chemistry. Prerequisite(s): courses 151A/L and 146B or graduate standing. The Staff

261. Foundations of Spectroscopy. *
The basic theory of time dependent processes is covered at an advanced level. The interaction of electromagnetic radiation and matter is described using both semiclassical and quantum field formulations. A variety of modern spectroscopic techniques are discussed both in terms of the basic processes and their use in the elucidation of chemical structure and dynamics. Prerequisite(s): course 163A. Offered in alternate academic years. J. Zhang

262. Statistical Mechanics. W
Theory and concepts of statistical mechanics with applications to ideal gases, condensed systems, phase transition, and non-equilibrium thermodynamics. Lecture: 3-1/2 hours. Prerequisite(s): course 160B or 163A. Offered in alternate academic years. I. Benjamin

263. Quantum Mechanics. W
A rigorous introductory course: the Schrödinger equation, operator formalism, matrix mechanics, angular momentum, and spin. Perturbation and other approximate methods. Applications to atomic and molecular problems. Lecture: 3-1/2 hours. Prerequisite(s): courses 163A and Physics 114A-B. Offered in alternate academic years. J. Zhang

265. Computer Simulation in Statistical Mechanics. *
A detailed introduction of the use of computer simulation methods in physical and biophysical chemistry. Includes review of thermodynamics and statistical mechanics, molecular mechanics, molecular dynamics, and Monte-Carlo methods. Applications to liquid structure, reaction dynamics, and protein dynamics. Offered in alternate academic years. I. Benjamin

266. Advanced Topics in Physical Chemistry.
A graduate course covering advanced topics in physical chemistry. Topics vary from year to year.

266A. Lasers and Their Chemical Applications. *
Introduces the basic theoretical principles of lasers and laser light. Various types of lasers and selected applications to chemistry are discussed. The use of lasers in photochemistry, spectroscopy, chemical kinetics, and chemical analysis is considered. Lecture: 3-1/2 hours. Prerequisite(s): course 163A and Physics 114A-B. Offered in alternate academic years. May be repeated for credit. The Staff

266B. Gas Phase Kinetics. *
A discussion of rate processes in gases. Descriptions of experimental and theoretical work on unimolecular, bimolecular, and termolecular reactions and energy transfer processes. Lecture: 3-1/2 hours. Prerequisite(s): course 262. Offered in alternate academic years. May be repeated for credit. The Staff

268. Solid State and Materials Chemistry. *
Topics include synthesis of solid-state materials and their characterization using experimental techniques: XRD, TEM spectroscopy, NMR, and their applications in technologies. Emphasis on new materials, e.g., polymer, biopolymers, nanomaterials, organic/inorganic composites, ceramics, superconductors, electronic, magnetic, and opto-electronic materials. Prerequisite(s): courses 163A and 163B. Enrollment restricted to senior and graduate chemistry majors. J. Zhang

269. Electrochemistry. F
Designed to introduce basic principles and applications of electrochemistry to students at upper undergraduate and lower graduate levels in various fields including analytical, physical, and materials chemistry. Enrollment restricted to seniors and graduate students. S. Chen

273. Applications of Symmetry and Quantum Mechanics. *
Group theory and quantum mechanics are applied to problems of the electronic structure and spectra of molecules. A variety of topics including molecular orbital theory, reactivity, electronic structure calculations, and spectroscopy are discussed. Lecture: 3-1/2 hours. Prerequisite(s): course 160B or163A. Offered in alternate academic years. E. Switkes

282. Proseminar: Synthetic Methods. F,W,S
Weekly meetings devoted to the study of asymmetric and/or enantio-selective synthesis of optically active organic compounds of biological and medicinal significance. Topics drawn from the current literature and the research interests of the participants. May be repeated for credit. B. Singaram

283. Proseminar in Physical Organic Chemistry. F,W,S
Weekly meetings devoted to the study of physical and mechanistic organic chemistry. Topics drawn from the current literature and the research experiences of the participants. May be repeated for credit. C. Bernasconi

284. Proseminar in Synthetic Organic Chemistry. F,W,S
Weekly meetings devoted to the study of synthetic organic chemistry. Topics drawn from the current literature and the research interests of the participants. May be repeated for credit. R. Braslau

285. Proseminar: Photobiochemistry and Photobiology. F,W,S
A detailed study of molecular mechanisms of light energy conversion and light-signal transduction processes in biological systems. Student participation in critical discussion of current literature examples are emphasized. Two-hour lecture and two-hour seminar weekly. Enrollment limited to 8. May be repeated for credit. R. Bogomolni

286. Proseminar in Natural Products Chemistry. F,W,S
Weekly meetings devoted to the study of natural products. Topics drawn from the current literature and research interests of the participants. May be repeated for credit. P. Crews

287. Proseminar in Protein Aggregation and Protein Deposition Diseases. F,W,S
A detailed study of various aspects of protein structure, folding, and aggregation in the context of the molecular mechanism of protein deposition diseases, with particular emphasis on Parkinson’s disease and amyloidosis and the techniques involved in elucidating these mechanisms. May be repeated for credit. A. Fink

288. Proseminar in Bioinorganic Chemistry. F,W,S
Weekly meetings devoted to inorganic and bioinorganic research. Topics are drawn from current literature. Papers and reviews are discussed. Participants also give short seminars on topics of their research interests. May be repeated for credit. T. Holman, P. Mascharak

289. Proseminar: Biophysical Chemistry. *
Weekly meetings devoted to a detailed study of the theory and applications of nuclear magnetic resonance spectroscopy and imaging and related spectroscopic techniques to problems in biophysical chemistry. Topics are drawn from the current research literature and the research experiences of the participants. Enrollment limited to 20. May be repeated for credit. T. Schleich

290. Proseminar in Computational Chemistry. F,W,S
Weekly meetings devoted to the study of computational chemistry. Topics include molecular modeling, synthesis planning, drug design, and others from current literature and research interests of the participants. The Staff

291A. Organic Chemistry Research Seminar. F,W,S
Open to chemistry graduate students interested in organic chemistry. Weekly meetings are held to hear both local and external speakers discuss their work. Enrollment restricted to graduate students. May be repeated for credit. (S) B. Singaram, (FW) R. Lokey

291B. Biochemistry and Molecular Biology Research Seminar. F,W,S
A weekly seminar series covering topics on the frontiers of biochemistry and molecular biology. The speakers include experts in these fields from other institutions. Enrollment restricted to graduate students. May be repeated for credit. (F) G. Millhauser, (W) T. Schleich, (S) A. Fink

291C. Inorganic Chemistry Research Seminar. F,W,S
For those interested in following the recent developments in the various areas of inorganic chemistry. External speakers; weekly discussion based on personal research or recent literature, led by the inorganic chemistry faculty, postdoctoral fellows, and students. Enrollment restricted to graduate students. May be repeated for credit. (F) T. Holman, (W) P. Mascharak, (S) S.Oliver

291D. Physical Chemistry Research Seminar. F,W,S
A weekly seminar series covering topics of current research in physical chemistry. Weekly meetings are held to hear both local and external speakers discuss their work. Enrollment restricted to graduate students. May be repeated for credit. (F) R. Anderson, (W) E. Switkes, (S) S. Chen

292. Seminar (2 credits). F
Enrollment restrictions: graduate standing or approval of the graduate adviser. E. Switkes

296. Teaching Chemistry (3 credits). F
University-level pedagogy in chemistry; examines the role of preparation, assessment, and feedback in teaching chemistry discussion and laboratory sections. Effective classroom techniques and organizational strategies discussed; oral presentations analyzed critically. Required of entering chemistry graduate students. D. Palleros

297. Independent Study. F,W,S
A topic will be studied with faculty tutorial assistance to satisfy a need for the student when a regular course is not available. Students submit petition to sponsoring agency. The Staff

299. Thesis Research. F,W,S
Students submit petition to sponsoring agency. The Staff